Inhibitory effect of coumarin and its analogs on insulin fibrillation /cytotoxicity is depend on oligomerization states of the protein

Looking through a historical lens, attention to the stabilization of pharmaceutical proteins/peptides has been dramatically increased. Human insulin is the most challenging and the most widely used pharmaceutical protein in the world. In this study, the protein and coumarin as a plant-derived phenol...

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Detalles Bibliográficos
Autores principales: Akbarian, Mohsen, Rezaie, Ehsan, Farjadian, Fatemeh, Bazyar, Zahra, Hosseini-Sarvari, Mona, Ara, Ehsan Malek, Mirhosseini, Seyed Ali, Amani, Jafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057281/
https://www.ncbi.nlm.nih.gov/pubmed/35517555
http://dx.doi.org/10.1039/d0ra07710k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057281/
https://www.ncbi.nlm.nih.gov/pubmed/35517555
http://dx.doi.org/10.1039/d0ra07710k

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