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Thermodynamics of selective serotonin reuptake inhibitors partitioning into 1,2-dioleoyl-sn-glycero-3-phosphocholine bilayers

Knowledge of thermodynamics of lipid membrane partitioning of amphiphilic drugs as well as their binding site within the membrane are of great relevance not only for understanding the drugs' pharmacology but also for the development and optimization of more potent drugs. In this study, the inte...

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Detalles Bibliográficos
Autores principales: Ngo, Dat T. N., Nguyen, Trinh Q., Huynh, Hieu K., Nguyen, Trang T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057331/
https://www.ncbi.nlm.nih.gov/pubmed/35518408
http://dx.doi.org/10.1039/d0ra07367a