Zinc(ii)-cyclen coordinative amphiphiles for enhanced gene delivery

In this study, we developed coordinative amphiphiles for use as novel non-viral DNA vectors. As a modification of a conventional cationic lipid structure, we replaced the cationic head with a zinc(ii)-1,4,7,10-tetraazacyclododecane (Zn-cyclen) complex as a phosphate-directing group, and used biocomp...

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Detalles Bibliográficos
Autores principales: Zhang, Yi-Mei, Zhang, Ji, Liu, Yan-Hong, Guo, Yu, Yu, Xiao-Qi, Huang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057412/
https://www.ncbi.nlm.nih.gov/pubmed/35515358
http://dx.doi.org/10.1039/d0ra08027f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057412/
https://www.ncbi.nlm.nih.gov/pubmed/35515358
http://dx.doi.org/10.1039/d0ra08027f

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