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An improved 4′-aminomethyltrioxsalen-based nucleic acid crosslinker for biotinylation of double-stranded DNA or RNA

Nucleic acid crosslinkers that covalently join complementary strands of DNA/RNA have applications in both pharmaceuticals and as biochemical probes. Psoralen is a popular crosslinking moiety that reacts with double stranded DNA and RNA upon exposure to longwave UV light. The commercially available c...

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Detalles Bibliográficos
Autores principales: Wielenberg, Kevin, Wang, Miao, Yang, Min, Ozer, Abdullah, Lis, John T., Lin, Hening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057442/
https://www.ncbi.nlm.nih.gov/pubmed/35515418
http://dx.doi.org/10.1039/d0ra07437c