Structural and conformational changes induced by missense variants in the zinc finger domains of GATA3 involved in breast cancer

Breast cancer (BC) is the main cancer in women having multiple receptor based tumour subtypes. Large scale genome sequencing studies of BC have identified several genes among which GATA3 is reported as a highly mutated gene followed by TP53 and PIK3CA. GATA3 is a crucial transcription factor, and wa...

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Detalles Bibliográficos
Autores principales: Kumar, Rakesh, Kumar, Rahul, Tanwar, Pranay, Deo, S. V. S., Mathur, Sandeep, Agarwal, Usha, Hussain, Showket
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057444/
https://www.ncbi.nlm.nih.gov/pubmed/35515377
http://dx.doi.org/10.1039/d0ra07786k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057444/
https://www.ncbi.nlm.nih.gov/pubmed/35515377
http://dx.doi.org/10.1039/d0ra07786k

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