Cargando…
Structural and conformational changes induced by missense variants in the zinc finger domains of GATA3 involved in breast cancer
Breast cancer (BC) is the main cancer in women having multiple receptor based tumour subtypes. Large scale genome sequencing studies of BC have identified several genes among which GATA3 is reported as a highly mutated gene followed by TP53 and PIK3CA. GATA3 is a crucial transcription factor, and wa...
Autores principales: | Kumar, Rakesh, Kumar, Rahul, Tanwar, Pranay, Deo, S. V. S., Mathur, Sandeep, Agarwal, Usha, Hussain, Showket |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057444/ https://www.ncbi.nlm.nih.gov/pubmed/35515377 http://dx.doi.org/10.1039/d0ra07786k |
Ejemplares similares
-
Whole exome sequencing identifies novel variants of PIK3CA and validation of hotspot mutation by droplet digital PCR in breast cancer among Indian population
por: Kumar, Rahul, et al.
Publicado: (2023) -
Impact of family medicine practice in combating Violence against Doctors
por: Tanwar, Pranay, et al.
Publicado: (2019) -
Peroxiredoxins - Urinary Surveillance Biomarkers in Urothelial Cancer
por: Kumari, Nitu, et al.
Publicado: (2022) -
Comprehensive mutations analyses of FTO (fat mass and obesity-associated gene) and their effects on FTO’s substrate binding implicated in obesity
por: Kumar, Rakesh, et al.
Publicado: (2022) -
Liquid Biopsies: Emerging role and clinical applications in solid tumours
por: Sisodiya, Sandeep, et al.
Publicado: (2023)