Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression

HDL cholesterol (HDL-C) predicts risk of cardiovascular disease (CVD), but the factors regulating HDL are incompletely understood. Emerging data link CVD risk to decreased HDL-C in 8% of the world population and 40% of East Asians who carry an SNP of aldehyde dehydrogenase 2 (ALDH2) rs671, responsib...

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Detalles Bibliográficos
Autores principales: Li, Luxiao, Zhong, Shanshan, Li, Rui, Liang, Ningning, Zhang, Lili, Xia, Shen, Xu, Xiaodong, Chen, Xin, Chen, Shiting, Tao, Yongzhen, Yin, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057588/
https://www.ncbi.nlm.nih.gov/pubmed/35393951
http://dx.doi.org/10.1172/jci.insight.155869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057588/
https://www.ncbi.nlm.nih.gov/pubmed/35393951
http://dx.doi.org/10.1172/jci.insight.155869

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