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Aldehyde dehydrogenase 2 and PARP1 interaction modulates hepatic HDL biogenesis by LXRα-mediated ABCA1 expression
HDL cholesterol (HDL-C) predicts risk of cardiovascular disease (CVD), but the factors regulating HDL are incompletely understood. Emerging data link CVD risk to decreased HDL-C in 8% of the world population and 40% of East Asians who carry an SNP of aldehyde dehydrogenase 2 (ALDH2) rs671, responsib...
Autores principales: | Li, Luxiao, Zhong, Shanshan, Li, Rui, Liang, Ningning, Zhang, Lili, Xia, Shen, Xu, Xiaodong, Chen, Xin, Chen, Shiting, Tao, Yongzhen, Yin, Huiyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057588/ https://www.ncbi.nlm.nih.gov/pubmed/35393951 http://dx.doi.org/10.1172/jci.insight.155869 |
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