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Mechanosensitive Piezo1 channels mediate renal fibrosis

Kidney fibrosis is the final common pathway of progressive kidney diseases, the underlying mechanisms of which are not fully understood. The purpose of the current study is to investigate a role of Piezo1, a mechanosensitive nonselective cation channel, in kidney fibrosis. In human fibrotic kidneys,...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaoduo, Kong, Yonglun, Liang, Baien, Xu, Jinhai, Lin, Yu, Zhou, Nan, Li, Jing, Jiang, Bin, Cheng, Jianding, Li, Chunling, Wang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057604/
https://www.ncbi.nlm.nih.gov/pubmed/35230979
http://dx.doi.org/10.1172/jci.insight.152330