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TET2 regulates immune tolerance in chronically activated mast cells

Mutation of the TET2 DNA-hydroxymethylase has been associated with a number of immune pathologies. The disparity in phenotype and clinical presentation among these pathologies leads to questions regarding the role of TET2 mutation in promoting disease evolution in different immune cell types. Here w...

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Detalles Bibliográficos
Autores principales: Rigo, Riccardo, Chelbi, Rabie, Agopian, Julie, Letard, Sebastien, Griffon, Aurélien, Ghamlouch, Hussein, Vernerey, Julien, Ladopoulos, Vasileios, Voisset, Edwige, De Sepulveda, Paulo, Guittard, Geoffrey, Nunès, Jacques A., Bidaut, Ghislain, Göttgens, Berthold, Weber, Michael, Bernard, Olivier A., Dubreuil, Patrice, Soucie, Erinn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057605/
https://www.ncbi.nlm.nih.gov/pubmed/35393954
http://dx.doi.org/10.1172/jci.insight.154191