Intranasal delivery of a small-molecule ErbB inhibitor promotes recovery from acute and late-stage CNS inflammation

Multiple sclerosis (MS) is an autoimmune inflammatory disease of the CNS that is characterized by demyelination and axonal degeneration. Although several established treatments reduce relapse burden, effective treatments to halt chronic progression are scarce. Single-cell transcriptomic studies in M...

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Detalles Bibliográficos
Autores principales: Linnerbauer, Mathias, Lößlein, Lena, Vandrey, Oliver, Tsaktanis, Thanos, Beer, Alexander, Naumann, Ulrike J., Panier, Franziska, Beyer, Tobias, Nirschl, Lucy, Kuramatsu, Joji B., Winkler, Jürgen, Quintana, Francisco J., Rothhammer, Veit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057609/
https://www.ncbi.nlm.nih.gov/pubmed/35393953
http://dx.doi.org/10.1172/jci.insight.154824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057609/
https://www.ncbi.nlm.nih.gov/pubmed/35393953
http://dx.doi.org/10.1172/jci.insight.154824

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