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Intact mitochondrial substrate efflux is essential for prevention of tubular injury in a sex-dependent manner

The importance of healthy mitochondrial function is implicated in the prevention of chronic kidney disease (CKD) and diabetic kidney disease (DKD). Sex differences also play important roles in DKD. Our previous studies revealed that mitochondrial substrate overload (modeled by homozygous deletion of...

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Detalles Bibliográficos
Autores principales: McCrimmon, Allison, Cahill, Kerin M., Kruger, Claudia, Mangelli, Margaret E., Bouffard, Emily, Dobroski, Timothy, Michanczyk, Kelly N., Burke, Susan J., Noland, Robert C., Ilatovskaya, Daria V., Stadler, Krisztian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057616/
https://www.ncbi.nlm.nih.gov/pubmed/35230975
http://dx.doi.org/10.1172/jci.insight.150696