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Intact mitochondrial substrate efflux is essential for prevention of tubular injury in a sex-dependent manner
The importance of healthy mitochondrial function is implicated in the prevention of chronic kidney disease (CKD) and diabetic kidney disease (DKD). Sex differences also play important roles in DKD. Our previous studies revealed that mitochondrial substrate overload (modeled by homozygous deletion of...
Autores principales: | McCrimmon, Allison, Cahill, Kerin M., Kruger, Claudia, Mangelli, Margaret E., Bouffard, Emily, Dobroski, Timothy, Michanczyk, Kelly N., Burke, Susan J., Noland, Robert C., Ilatovskaya, Daria V., Stadler, Krisztian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057616/ https://www.ncbi.nlm.nih.gov/pubmed/35230975 http://dx.doi.org/10.1172/jci.insight.150696 |
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