Labile iron accumulation augments T follicular helper cell differentiation

T follicular helper (Tfh) cells are a subset of CD4(+) T cells that are essential in the pathogenesis of systemic lupus erythematosus (SLE). Notably, iron is required for activated CD4(+) T lymphocytes to sustain high proliferation and metabolism. In this issue of the JCI, Gao et al. showed that CD4...

Descripción completa

Detalles Bibliográficos
Autores principales: Scindia, Yogesh, Mehrad, Borna, Morel, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057622/
https://www.ncbi.nlm.nih.gov/pubmed/35499081
http://dx.doi.org/10.1172/JCI159472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057622/
https://www.ncbi.nlm.nih.gov/pubmed/35499081
http://dx.doi.org/10.1172/JCI159472

Ejemplares similares