KLF5 protects the intestinal epithelium against Th17 immune response in a murine colitis model

Inflammatory bowel disease (IBD) is a chronic illness characterized by dysregulated immune cascades in the intestines, in which the Th17 immune response plays an important role. We demonstrated that mice with intestinal epithelium–specific deletion of Krüppel-like factor 5 (Klf5) developed Th17-depe...

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Detalles Bibliográficos
Autores principales: Shieh, Jason, Chu, Timothy H., Liu, Yang, Kim, Julie, Ruiz de Sabando, Ainara, Kobayashi, Soma, Zee, Sui Y., Sheridan, Brian S., Bialkowska, Agnieszka B., Yang, Vincent W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057631/
https://www.ncbi.nlm.nih.gov/pubmed/35393949
http://dx.doi.org/10.1172/jci.insight.153488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057631/
https://www.ncbi.nlm.nih.gov/pubmed/35393949
http://dx.doi.org/10.1172/jci.insight.153488

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