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FLT3 mutations in acute myeloid leukemia: a review focusing on clinically applicable drugs

FMS-like tyrosine kinase 3 (FLT3) mutations, the most frequently detected genetic aberrations in patients with acute myeloid leukemia (AML), are identified in approximately 30% of patients with newly diagnosed AML and are more common in patients with normal karyotypes. Since the discovery of FLT3 mu...

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Detalles Bibliográficos
Autores principales: Ahn, Jae-Sook, Kim, Hyeoung-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057665/
https://www.ncbi.nlm.nih.gov/pubmed/35483923
http://dx.doi.org/10.5045/br.2022.2022017