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2′-O-Methyl molecular beacon: a promising molecular tool that permits elimination of sticky-end pairing and improvement of detection sensitivity
An innovative 2′-O-methyl molecular beacon (MB) has been designed and prepared with improved thermal stability and unique nuclease resistance. The employment of 2′-O-methyl MBs helps efficiently suppress the background signal, while DNase I is responsible for the signal amplification and elimination...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057772/ https://www.ncbi.nlm.nih.gov/pubmed/35516551 http://dx.doi.org/10.1039/d0ra07341e |