A brain glioma gene delivery strategy by angiopep-2 and TAT-modified magnetic lipid-polymer hybrid nanoparticles

Owing to the existence of the blood–brain barrier (BBB), most treatments cannot achieve significant effects on gliomas. In this study, synergistic multitarget Ang-TAT-Fe(3)O(4)-pDNA-(ss)373 lipid-polymer hybrid nanoparticles (LPNPs) were designed to penetrate the BBB and deliver therapeutic genes to...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiao, Lanxin, Qin, Yu, Wang, Yaxin, Liang, Yi, Zhu, Dunwan, Xiong, Wei, Li, Lu, Bao, Di, Zhang, Linhua, Jin, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057840/
https://www.ncbi.nlm.nih.gov/pubmed/35516547
http://dx.doi.org/10.1039/d0ra07161g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057840/
https://www.ncbi.nlm.nih.gov/pubmed/35516547
http://dx.doi.org/10.1039/d0ra07161g

Ejemplares similares