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Pre-existing T cell immunity determines the frequency and magnitude of cellular immune response to two doses of mRNA vaccine against SARS-CoV-2

Little is known about the factors associated with lack of T-cell response to mRNA vaccines against SARS-CoV-2. In a prospective cohort of 61 health care workers (HCWs), 21% and 16% after the first dose of mRNA BNT162b vaccine, and 12% and 7% after the second dose, showed lack of CD4(+) and CD8(+) T-...

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Detalles Bibliográficos
Autores principales: Casado, José L., Vizcarra, Pilar, Haemmerle, Johannes, Velasco, Héctor, Martín-Hondarza, Adrián, Rodríguez-Domínguez, Mario J., Velasco, Tamara, Martín, Sara, Romero-Hernández, Beatriz, Fernández-Escribano, Marina, Vallejo, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9057925/
https://www.ncbi.nlm.nih.gov/pubmed/35529539
http://dx.doi.org/10.1016/j.jvacx.2022.100165