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Enantioselective amination of 4-alkylisoquinoline-1,3(2H,4H)-dione derivatives

A mild and efficient enantioselective amination of 4-alkylisoquinoline-1,3(2H,4H)-dione derivatives was established, which is compatible with a broad range of substrates and delivers the final products in excellent yields (up to 99%) and ee values (up to 99%) with low catalyst loading (down to 1 mol...

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Detalles Bibliográficos
Autores principales: Cheng, Cheng, Li, Ying-Xian, Jia, Xue-Min, Zhang, Ji-Quan, Zhao, Yong-Long, Feng, Wei, Tang, Lei, Yang, Yuan-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058008/
https://www.ncbi.nlm.nih.gov/pubmed/35514906
http://dx.doi.org/10.1039/d0ra07806a