In silico approach: biological prediction of nordentatin derivatives as anticancer agent inhibitors in the cAMP pathway

A combination of computational techniques has been carried out to predict the binding of nordentatin derivatives based on pyranocoumarin semi-synthesis with the target protein from the expression of the PDE4B gene. The inhibition of the cAMP pathway is the main target of anti-cancer drugs, which is...

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Detalles Bibliográficos
Autores principales: Abdjan, Muhammad Ikhlas, Aminah, Nanik Siti, Siswanto, Imam, Thant, Tin Myo, Kristanti, Alfinda Novi, Takaya, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058016/
https://www.ncbi.nlm.nih.gov/pubmed/35514899
http://dx.doi.org/10.1039/d0ra07838g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058016/
https://www.ncbi.nlm.nih.gov/pubmed/35514899
http://dx.doi.org/10.1039/d0ra07838g

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