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In silico approach: biological prediction of nordentatin derivatives as anticancer agent inhibitors in the cAMP pathway
A combination of computational techniques has been carried out to predict the binding of nordentatin derivatives based on pyranocoumarin semi-synthesis with the target protein from the expression of the PDE4B gene. The inhibition of the cAMP pathway is the main target of anti-cancer drugs, which is...
Autores principales: | Abdjan, Muhammad Ikhlas, Aminah, Nanik Siti, Siswanto, Imam, Thant, Tin Myo, Kristanti, Alfinda Novi, Takaya, Yoshiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058016/ https://www.ncbi.nlm.nih.gov/pubmed/35514899 http://dx.doi.org/10.1039/d0ra07838g |
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