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Synthesis of novel naphthalene-heterocycle hybrids with potent antitumor, anti-inflammatory and antituberculosis activities

Multitarget-directed drugs (hybrid drugs) constitute an efficient avenue for the treatment of multifactorial diseases. In this work, novel naphthalene hybrids with different heterocyclic scaffolds such as nicotinonitrile, pyran, pyranopyrazole, pyrazole, pyrazolopyridine, and azepine were efficientl...

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Detalles Bibliográficos
Autores principales: Abozeid, Mohamed Ahmed, El-Sawi, Aya Atef, Abdelmoteleb, Mohamed, Awad, Hanem, Abdel-Aziz, Marwa Mostafa, Hassan Abdel-Rahman, Abdel-Rahman, Ibrahim El-Desoky, El-Sayed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058152/
https://www.ncbi.nlm.nih.gov/pubmed/35514936
http://dx.doi.org/10.1039/d0ra08526j