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PD‐L1 expressed from tumor cells promotes tumor growth and invasion in lung cancer via modulating TGF‐β1/SMAD4 expression

BACKGROUND: Programmed death ligand‐1 (PD‐L1) has a known association with the prognosis of human cancers because of its ability to alter tumor immune surveillance via its interaction with PD‐1. We questioned whether expression of PD‐L1 in tumor cells could directly promote tumor growth and invasive...

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Detalles Bibliográficos
Autores principales: Chen, Ming‐Jenn, Wang, Yao‐Chen, Wang, Lee, Shen, Ching‐Ju, Chen, Chih‐Yi, Lee, Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058315/
https://www.ncbi.nlm.nih.gov/pubmed/35373505
http://dx.doi.org/10.1111/1759-7714.14388