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Copper mediated one-pot synthesis of quinazolinones and exploration of piperazine linked quinazoline derivatives as anti-mycobacterial agents

A facile method was developed for the synthesis of quinazolinone derivatives in a one-pot condensation reaction via in situ amine generation using ammonia as the amine source and with the formation of four new C–N bonds in good to excellent yields. With the optimised method, we synthesized a library...

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Detalles Bibliográficos
Autores principales: Malasala, Satyaveni, Gour, Jitendra, Ahmad, Md. Naiyaz, Gatadi, Srikanth, Shukla, Manjulika, Kaul, Grace, Dasgupta, Arunava, Madhavi, Y. V., Chopra, Sidharth, Nanduri, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058414/
https://www.ncbi.nlm.nih.gov/pubmed/35519697
http://dx.doi.org/10.1039/d0ra08644d