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Effects of mTORC1 inhibition on proteasome activity and levels

The mechanistic target of rapamycin (mTOR) regulates numerous extracellular and intracellular signals involved in the maintenan-ce of cellular homeostasis and cell growth. mTOR also functions as an endogenous inhibitor of autophagy. Under nutrient-rich conditions, mTOR complex 1 (mTORC1) phosphoryla...

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Detalles Bibliográficos
Autores principales: Park, Seo Hyeong, Choi, Won Hoon, Lee, Min Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058467/
https://www.ncbi.nlm.nih.gov/pubmed/35321785
http://dx.doi.org/10.5483/BMBRep.2022.55.4.032