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Reactive microglia and mitochondrial unfolded protein response following ventriculomegaly and behavior defects in kaolin-induced hydrocephalus

Ventriculomegaly induced by the abnormal accumulation of cerebrospinal fluid (CSF) leads to hydrocephalus, which is accompanied by neuroinflammation and mitochondrial oxidative stress. The mitochondrial stress activates mitochondrial unfolded protein response (UPRmt), which is essential for mitochon...

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Detalles Bibliográficos
Autores principales: Zhu, Jiebo, Lee, Min Joung, Chang, Hee Jin, Ju, Xianshu, Cui, Jianchen, Lee, Yu Lim, Go, Dahyun, Chung, Woosuk, Oh, Eungseok, Heo, Jun Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058473/
https://www.ncbi.nlm.nih.gov/pubmed/34903317
http://dx.doi.org/10.5483/BMBRep.2022.55.4.126