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Notch-dependent DNA cis-regulatory elements and their dose-dependent control of C. elegans stem cell self-renewal

A long-standing biological question is how DNA cis-regulatory elements shape transcriptional patterns during metazoan development. Reporter constructs, cell culture assays and computational modeling have made major contributions to answering this question, but analysis of elements in their natural c...

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Detalles Bibliográficos
Autores principales: Lynch, Tina R., Xue, Mingyu, Czerniak, Cazza W., Lee, ChangHwan, Kimble, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058496/
https://www.ncbi.nlm.nih.gov/pubmed/35394007
http://dx.doi.org/10.1242/dev.200332