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The importance of Asn52 in the structure–function relationship of human cytochrome c

The function of the highly conserved residue Asn52 in human cytochrome c (H-Cyt c) is not fully understood. Herein, we show that the naturally occurring variant N52S H-Cyt c has a perturbed secondary structure, with a small fraction of high-spin species. Remarkably, it exhibits an enhanced peroxidas...

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Detalles Bibliográficos
Autores principales: Lou, Dan, Liu, Xi-Chun, Wang, Xiao-Juan, Gao, Shu-Qin, Wen, Ge-Bo, Lin, Ying-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058552/
https://www.ncbi.nlm.nih.gov/pubmed/35516242
http://dx.doi.org/10.1039/d0ra09961a