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Circular and linear: a tale of aptamer selection for the activation of SIRT1 to induce death in cancer cells

It is a challenge to select the right target to treat conditions without affecting non-diseased cells. Cancer belongs to the top 10 causes of death in the world and it remains difficult to treat. Amongst cancer emerging targets, silent information regulator 1 (SIRT1) – a histone deacetylase – has sh...

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Detalles Bibliográficos
Autores principales: Al-Sudani, Basma, Ragazzon-Smith, Abby H., Aziz, Athar, Alansari, Rania, Ferry, Natalie, Krstic-Demonacos, Marija, Ragazzon, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058605/
https://www.ncbi.nlm.nih.gov/pubmed/35516259
http://dx.doi.org/10.1039/d0ra07857c