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Circular and linear: a tale of aptamer selection for the activation of SIRT1 to induce death in cancer cells
It is a challenge to select the right target to treat conditions without affecting non-diseased cells. Cancer belongs to the top 10 causes of death in the world and it remains difficult to treat. Amongst cancer emerging targets, silent information regulator 1 (SIRT1) – a histone deacetylase – has sh...
Autores principales: | Al-Sudani, Basma, Ragazzon-Smith, Abby H., Aziz, Athar, Alansari, Rania, Ferry, Natalie, Krstic-Demonacos, Marija, Ragazzon, Patricia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058605/ https://www.ncbi.nlm.nih.gov/pubmed/35516259 http://dx.doi.org/10.1039/d0ra07857c |
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