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pH-sensitive zwitterionic polycarboxybetaine as a potential non-viral vector for small interfering RNA delivery

Small interfering RNA (siRNA) has great potential for the treatment of various diseases. However, its intrinsic deficiencies seriously limit its application. Herein, pH-sensitive zwitterionic polymer polycarboxybetaine (PCB) was developed as a non-viral vector for siRNA. The PCB could be protonated...

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Detalles Bibliográficos
Autores principales: Peng, Huan, Ji, Weihong, Zhao, Ruichen, Lu, Zhiguo, Yang, Jun, Li, Yan, Zhang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058814/
https://www.ncbi.nlm.nih.gov/pubmed/35516239
http://dx.doi.org/10.1039/d0ra09359a