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pH-sensitive zwitterionic polycarboxybetaine as a potential non-viral vector for small interfering RNA delivery
Small interfering RNA (siRNA) has great potential for the treatment of various diseases. However, its intrinsic deficiencies seriously limit its application. Herein, pH-sensitive zwitterionic polymer polycarboxybetaine (PCB) was developed as a non-viral vector for siRNA. The PCB could be protonated...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058814/ https://www.ncbi.nlm.nih.gov/pubmed/35516239 http://dx.doi.org/10.1039/d0ra09359a |