A hybrid approach unveils drug repurposing candidates targeting an Alzheimer pathophysiology mechanism

The high number of failed pre-clinical and clinical studies for compounds targeting Alzheimer disease (AD) has demonstrated that there is a need to reassess existing strategies. Here, we pursue a holistic, mechanism-centric drug repurposing approach combining computational analytics and experimental...

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Detalles Bibliográficos
Autores principales: Lage-Rupprecht, Vanessa, Schultz, Bruce, Dick, Justus, Namysl, Marcin, Zaliani, Andrea, Gebel, Stephan, Pless, Ole, Reinshagen, Jeanette, Ellinger, Bernhard, Ebeling, Christian, Esser, Alexander, Jacobs, Marc, Claussen, Carsten, Hofmann-Apitius, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058900/
https://www.ncbi.nlm.nih.gov/pubmed/35510183
http://dx.doi.org/10.1016/j.patter.2021.100433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9058900/
https://www.ncbi.nlm.nih.gov/pubmed/35510183
http://dx.doi.org/10.1016/j.patter.2021.100433

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