Data-Driven Derivation of Molecular Substructures That Enhance Drug Activity in Gram-Negative Bacteria

[Image: see text] The complex cell envelope of Gram-negative bacteria creates a formidable barrier to antibiotic influx. Reduced drug uptake impedes drug development and contributes to a wide range of drug-resistant bacterial infections, including those caused by extremely resistant species prioriti...

Descripción completa

Detalles Bibliográficos
Autores principales: Gurvic, Dominik, Leach, Andrew G., Zachariae, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059115/
https://www.ncbi.nlm.nih.gov/pubmed/35427114
http://dx.doi.org/10.1021/acs.jmedchem.1c01984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059115/
https://www.ncbi.nlm.nih.gov/pubmed/35427114
http://dx.doi.org/10.1021/acs.jmedchem.1c01984

Ejemplares similares