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Data-Driven Derivation of Molecular Substructures That Enhance Drug Activity in Gram-Negative Bacteria
[Image: see text] The complex cell envelope of Gram-negative bacteria creates a formidable barrier to antibiotic influx. Reduced drug uptake impedes drug development and contributes to a wide range of drug-resistant bacterial infections, including those caused by extremely resistant species prioriti...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059115/ https://www.ncbi.nlm.nih.gov/pubmed/35427114 http://dx.doi.org/10.1021/acs.jmedchem.1c01984 |