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On the Utility of Chemical Strategies to Improve Peptide Gut Stability
[Image: see text] Inherent susceptibility of peptides to enzymatic degradation in the gastrointestinal tract is a key bottleneck in oral peptide drug development. Here, we present a systematic analysis of (i) the gut stability of disulfide-rich peptide scaffolds, orally administered peptide therapeu...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059125/ https://www.ncbi.nlm.nih.gov/pubmed/35420805 http://dx.doi.org/10.1021/acs.jmedchem.2c00094 |