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Mechanism of Osmolyte Stabilization–Destabilization of Proteins: Experimental Evidence
[Image: see text] In this work, we investigated the influence of stabilizing (N,N,N-trimethylglycine) and destabilizing (urea) osmolytes on the hydration spheres of biomacromolecules in folded forms (trpzip-1 peptide and hen egg white lysozyme—hewl) and unfolded protein models (glycine—GLY and N-met...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059127/ https://www.ncbi.nlm.nih.gov/pubmed/35441516 http://dx.doi.org/10.1021/acs.jpcb.2c00281 |