The potential role of the 5,6-dihydropyridin-2(1H)-one unit of piperlongumine on the anticancer activity

Piperlongumine (PL), a potent anticancer agent from the plant long pepper (Piper longum), contains the 5,6-dihydropyridin-2(1H)-one heterocyclic scaffold and cinnamoyl unit. In this paper, we synthesized a series of PL analogs and evaluated their cytotoxicity against cancer cells for the sake of exp...

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Detalles Bibliográficos
Autores principales: Mu, Wen-Wen, Li, Peng-Xiao, Liu, Yue, Yang, Jie, Liu, Guo-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059148/
https://www.ncbi.nlm.nih.gov/pubmed/35516728
http://dx.doi.org/10.1039/d0ra08778e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059148/
https://www.ncbi.nlm.nih.gov/pubmed/35516728
http://dx.doi.org/10.1039/d0ra08778e

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