Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells

Understanding metabolic pathways that regulate Th17 development is important to broaden therapeutic options for Th17-mediated autoimmunity. Here, we report a pivotal role of mitochondrial oxidative phosphorylation (OXPHOS) for lineage specification toward pathogenic Th17 differentiation. Th17 cells...

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Detalles Bibliográficos
Autores principales: Shin, Boyoung, Benavides, Gloria A., Geng, Jianlin, Koralov, Sergei B., Hu, Hui, Darley-Usmar, Victor M., Harrington, Laurie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059282/
https://www.ncbi.nlm.nih.gov/pubmed/32049019
http://dx.doi.org/10.1016/j.celrep.2020.01.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059282/
https://www.ncbi.nlm.nih.gov/pubmed/32049019
http://dx.doi.org/10.1016/j.celrep.2020.01.022

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