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Lactate Transporter SLC16A3 (MCT4) as an Onco-Immunological Biomarker Associating Tumor Microenvironment and Immune Responses in Lung Cancer

PURPOSE: Lactate, a marker of tumor metabolic reprogramming, maintains the acidic microenvironment and also affects the metabolism and function of immune cells. SLC16A3 is responsible for the extracellular transport of lactate, which is a key component of glycolysis. However, the role of SLC16A3 in...

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Detalles Bibliográficos
Autores principales: Tao, Qingsong, Li, Xin, Zhu, Ting, Ge, Xiaoqin, Gong, Shengping, Guo, Jianxin, Ma, Ruishuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059363/
https://www.ncbi.nlm.nih.gov/pubmed/35509603
http://dx.doi.org/10.2147/IJGM.S353592