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The LPA-CDK5-tau pathway mediates neuronal injury in an in vitro model of ischemia-reperfusion insult

Lysophosphatidic acid (LPA) is a common glycerol phospholipid and an important extracellular signaling molecule. LPA binds to its receptors and mediates a variety of biological effects, including the pathophysiological process underlying ischemic brain damage and traumatic brain injury. However, the...

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Detalles Bibliográficos
Autores principales: Wang, Yaya, Zhang, Jie, Huang, Liqin, Mo, Yanhong, Wang, Changyu, Li, Yiyi, Zhang, Yangyang, Zhang, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059403/
https://www.ncbi.nlm.nih.gov/pubmed/35501719
http://dx.doi.org/10.1186/s12883-022-02694-2