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miRNA‐34c Suppresses Osteosarcoma Progression In Vivo by Targeting Notch and E2F

The expression of microRNAs (miRNAs) is dysregulated in many types of cancers including osteosarcoma (OS) due to genetic and epigenetic alterations. Among these, miR‐34c, an effector of tumor suppressor P53 and an upstream negative regulator of Notch signaling in osteoblast differentiation, is dysre...

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Detalles Bibliográficos
Autores principales: Bae, Yangjin, Zeng, Huan‐Chang, Chen, Yi‐Ting, Ketkar, Shamika, Munivez, Elda, Yu, Zhiyin, Gannon, Francis H., Lee, Brendan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059472/
https://www.ncbi.nlm.nih.gov/pubmed/35509638
http://dx.doi.org/10.1002/jbm4.10623