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Genetic Deletion of Menin in Mouse Mesenchymal Stem Cells: An Experimental and Computational Analysis

Loss‐of‐function mutations in the MEN1 tumor‐suppressor gene cause the multiple endocrine neoplasia type 1 syndrome. Menin, the MEN1 gene product, is expressed in many tissues, including bone, where its function remains elusive. We conditionally inactivated menin in mesenchymal stem cells (MSCs) usi...

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Detalles Bibliográficos
Autores principales: Abi‐Rafeh, Jad, Asgari, Meisam, Troka, Ildi, Canaff, Lucie, Moussa, Ahmed, Pasini, Damiano, Goltzman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059475/
https://www.ncbi.nlm.nih.gov/pubmed/35509630
http://dx.doi.org/10.1002/jbm4.10622