Differences between the binding modes of enantiomers S/R-nicotine to acetylcholinesterase

Nicotine causes neurotoxic effects because it quickly penetrates the blood–brain barrier after entering the human body. Acetylcholinesterase (AChE) is a key enzyme in the central and peripheral nervous system associated with neurotoxicity. In this study, a spectroscopic method and computer simulatio...

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Detalles Bibliográficos
Autores principales: Yang, Ji, Chen, Yongkuan, Liu, Zhihua, Yang, Liu, Tang, Jianguo, Miao, Mingming, Gan, Na, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059617/
https://www.ncbi.nlm.nih.gov/pubmed/35518031
http://dx.doi.org/10.1039/c8ra09963d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059617/
https://www.ncbi.nlm.nih.gov/pubmed/35518031
http://dx.doi.org/10.1039/c8ra09963d

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