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Differences between the binding modes of enantiomers S/R-nicotine to acetylcholinesterase
Nicotine causes neurotoxic effects because it quickly penetrates the blood–brain barrier after entering the human body. Acetylcholinesterase (AChE) is a key enzyme in the central and peripheral nervous system associated with neurotoxicity. In this study, a spectroscopic method and computer simulatio...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059617/ https://www.ncbi.nlm.nih.gov/pubmed/35518031 http://dx.doi.org/10.1039/c8ra09963d |