Design, synthesis and broad-spectrum Bcr-Abl inhibitory activity of novel thiazolamide–benzamide derivatives

Bcr-Abl plays an important role in the pathogenesis and development of chronic myeloid leukemia (CML). But Bcr-Abl is prone to mutation, so it increases the difficulty of clinical treatment. Therefore, it is crucial to design a new class of broad-spectrum Bcr-Abl inhibitors. Herein, forty novel thia...

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Detalles Bibliográficos
Autores principales: Liu, Juan, Huang, Honglin, Deng, Xiangping, Xiong, Runde, Cao, Xuan, Tang, Guotao, Wu, Xin, Xu, Shiyu, Peng, Junmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059735/
https://www.ncbi.nlm.nih.gov/pubmed/35516138
http://dx.doi.org/10.1039/c8ra10096a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059735/
https://www.ncbi.nlm.nih.gov/pubmed/35516138
http://dx.doi.org/10.1039/c8ra10096a

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