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Chronic psychological stress alters gene expression in rat colon epithelial cells promoting chromatin remodeling, barrier dysfunction and inflammation

Chronic stress is commonly associated with enhanced abdominal pain (visceral hypersensitivity), but the cellular mechanisms underlying how chronic stress induces visceral hypersensitivity are poorly understood. In this study, we examined changes in gene expression in colon epithelial cells from a ra...

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Detalles Bibliográficos
Autores principales: Wiley, John W., Higgins, Gerald A., Hong, Shuangsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059753/
https://www.ncbi.nlm.nih.gov/pubmed/35509963
http://dx.doi.org/10.7717/peerj.13287