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DNA–affibody nanoparticle delivery system for cisplatin-based breast cancer chemotherapy

Cisplatin is the most widely used anticancer drug, but its side effects limit the maximum systemic dose. To circumvent the side effects, a DNA tetrahedron–affibody nanoparticle was prepared by combination of a DNA chain with cisplatin via interstrand crosslinks or adducts. Each nanocarrier can bind...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Zhang, HongLei, Han, MengNan, Yang, XueLi, Pei, ChaoHong, Xu, ZhiDong, Du, Jie, Li, Wei, Chen, Shengxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059769/
https://www.ncbi.nlm.nih.gov/pubmed/35516156
http://dx.doi.org/10.1039/c8ra08735k