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Synthesis of 4-(1H-isochromen-1-yl)isoquinolines through the silver-catalysed homodimerization of ortho-alkynylarylaldehydes and subsequent condensation of the 1,5-dicarbonyl motif with NH(3)

4-(1H-Isochromen-1-yl)isoquinoline derivatives were synthesized in high yields via the AgBF(4)-catalyzed self-reaction of ortho-alkynylarylaldehydes to give isochromene intermediates, followed by the dehydration of the 1,5-dicarbonyl motif with NH(3). Compared with electron-rich aromatic substituent...

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Detalles Bibliográficos
Autores principales: Guo, Minghui, Meng, Xin, Zhao, Yang, Dong, Yuexia, Sun, Xuejun, Tian, Laijin, Cao, Ziping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059814/
https://www.ncbi.nlm.nih.gov/pubmed/35520496
http://dx.doi.org/10.1039/c8ra09269a