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Synthesis of 4-(1H-isochromen-1-yl)isoquinolines through the silver-catalysed homodimerization of ortho-alkynylarylaldehydes and subsequent condensation of the 1,5-dicarbonyl motif with NH(3)
4-(1H-Isochromen-1-yl)isoquinoline derivatives were synthesized in high yields via the AgBF(4)-catalyzed self-reaction of ortho-alkynylarylaldehydes to give isochromene intermediates, followed by the dehydration of the 1,5-dicarbonyl motif with NH(3). Compared with electron-rich aromatic substituent...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059814/ https://www.ncbi.nlm.nih.gov/pubmed/35520496 http://dx.doi.org/10.1039/c8ra09269a |